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Programme
Thursday, September 4, 2003 -
Friday,
September 5, 2003 -
Saturday,
September 6, 2003
8.30 – 9.00
Room K1/K2 |
Transmission and early
manifestations |
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| Chairpersons: |
B. Drumm, Ireland
D. Danielsson, Sweden |
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State of the Art lecture
S. Czinn, United States |
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| 9.00 – 12.05 |
Focus/Round Tables |
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Epidemiology
H. Malaty, United States
Transmission and Clinic
B. Gold, United States |
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| 10.05 – 10.35 |
Coffee Break |
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Immunology
A.M.Svennerholm, SwedenMicrobial
Factors
T. Meyer, Germany
General Discussion |
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| 12.05 – 13.30 |
Individual Lunch &
Poster Viewing |
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13.30 – 17.00
Room K11 |
Workshop 1: Pediatric
Issues and Diagnosis |
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Chairpersons:
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Sybille Koletzko, Germany
Thomas Casswall, Sweden |
| Reporter: |
Hilpi Rautelin, Finland |
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15.01
IL1RN polymorphism and infection by H. pylori cagA
strains are risk factors for developing duodenal ulcer in children
D. M. M. Queiroz1, J. B. Guerra1, A. G.
Oliveira1,2, A. M. C. Rocha1, G. A. Rocha1,
A. S. T. Carvalho1, P. Bittencourt3, C. A.
Oliveira1;
1Universidade Federal de Minas Gerais, Faculdade de Medicina,
Belo Horizonte, Brazil, 2Faculdade de Medicina do Triângulo
Mineiro, Uberaba, Brazil, 3Universidade Federal de Minas
Gerais, Hospital das Clínicas, Belo Horizonte, Brazil.
15.02
Results of data collected by the Paediatric European Register
for Treatment of Helicobacter Pylori (PERTH)
G. Oderda;
Università Piemonte Orientale, Novara, Italy.
15.04
Prospective study to determine correlation of Helicobacter pylori
genotypes with ethnicity and after treatment outcome
R. A. Abdelhadi, R. Podzorski, D. Podzorski, M. F. El-Baba, S.
Madani, C. Lin, V. Tolia;
Children's Hospital of Michigan, Detroit, MI, United States.
15.07
Helicobacter pylori infection and abdominal symptoms in adolescents:
2-year prospective study
O. V. Reshetnikov1, S. A. Kurilovich1, I.
N. Tereshonok1, V. M. Häivä2, C. Granberg2;
1Institute of Internal Medicine, Novosibirsk, Russian
Federation, 2Orion Corporation, Orion Diagnostica, Espoo,
Finland.
17.01
Accuracy of 13C Breath Test (UBT) and Stool Antigen Test (ST)
during Proton Pump Inhibitors (PPIs) in H pylori (HP)
L. Gatta1, N. Vakil2, C. Ricci1,
A. Tampieri1, F. Perna1, M. Miglioli1,
D. Vaira1;
1S. Orsola Hospital, Bologna, Italy, 2GI Unit,
Milwaukee, WI, United States.
17.04
Validation of a new portable near patient urea breath test; The
Heliprobe system
W. A. de Boer1, C. van Alfen1, J. Rydén2;
1Ziekenhuis Bernhoven, dept of Internal Medicine, Oss,
Netherlands, 2Noster System AB, Stockholm, Sweden.
17.05
Detection of Helicobacter pylori infection and determination of
clarithromycin resistance in stool specimens by real-time PCR
C. Schabereiter-Gurtner1, B. Dragosics2, S.
Puz1, Z. Kovách1, A. M. Hirschl1, A.
Makristathis1;
1Department of Clinical Microbiology, Institute of Hygiene
and Medical Microbiology of the University of Vienna, Vienna, Austria,
2The Ambulatory Care Centre South, Regional Public Medical
Insurance Agency, Vienna, Austria.
15.06
Evaluation of a novel rapid one-step monoclonal immunochromatographic
assay for detection of H. pylori antigen in stool in children
D. Antos1, J. Crone2, N. Konstantopoulos1,
S. Koletzko1;
1Kinderpoliklinik, Dr. v. Haunersches Kinderspital, Muenchen,
Germany, 2University Children's Hospital, Vienna, Germany.
17.03
New rapid One Step Stool Antigen Test for diagnosing and monitoring H
pylori (HP) infection
L. Gatta, F. Perna, C. Ricci, A. Tampieri, M. Miglioli, D. Vaira;
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| 15.30 – 16.00 |
Coffee Break |
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| 16.00 – 17.00 |
Poster Discussion |
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13.30 – 17.00
Room K21 |
Workshop 2:
Inflammation vs host response |
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| Chairpersons: |
Jean Crabtree, United
Kingdom
Marianne Quiding-Järbrink, Sweden |
| Reporter: |
Richard Ferrero, France |
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04.06
A pro-inflammatory genetic profile increases the risk of chronic
atrophic gastritis and gastric carcinoma
C. Figueiredo, P. Canedo, M. L. Campos, C. C. Alves, G. Regalo,
J. C. Machado;
Institute of Molecular Pathology and Immunology of the University of
Porto - IPATIMUP, Porto, Portugal.
04.09
Tumor Necrosis Factor Alpha, Interferon Gamma, IL10 Host Gene
Polymorphisms And H. Pylori Infection
C. F. Zambon1, F. Navaglia2, D. Basso2,
N. Gallo2, A. Falda2, E. Greco2, P.
Fogar1, F. Farinati3, C. Belluco4, R.
Cardin3, D. Nitti4, M. Rugge5, F. Di
Mario6, M. Plebani2;
1Department of Medical and Surgical Sciences, University of
Padova, Padova, Italy, 2Department of Laboratory Medicine,
University of Padova, Padova, Italy, 3Gastroenterology,
University of Padova, Padova, Italy, 4Department of
Oncological and Surgical Sciences, University of Padova, Padova, Italy,
5Pathology, University of Padova, Padova, Italy, 6Gastroenterology,
University of Parma, Parma, Italy.
04.07
Comparison of the initial immune response towards recombinant urease A/B
and the H. pylori outer membrane proteins HpaA and Omp18 in vitro
P. Voland, N. Hafsi, C. K. Prinz;
II. Medical Department, Munich, Germany.
08.01
Studies on the mechanism of vaccine induced protection: transcriptional
profiling analysis of mice immunised against H. pylori.
A. K. Walduck1, A. Schmitt1, B. Lucas2,
T. F. Meyer1, T. Aebischer1;
1MPI for Infection Biology, Berlin, Germany, 2Laboratoire
de Virologie, Centre Hospitalier Regional Universitaire, Lille, France.
08.02
Immunisation with mucus-associated bacteria of the intestine, including
Helicobacter species, as a novel approach to the prevention and
amelioration of inflammatory bowel disease
S. J. Danon1, L. Zhang2, A. Lee2, J. G.
Fox3, H. M. Mitchell2;
1CSIRO Division of Molecular Science, Sydney, Australia,
2University of NSW, Sydney, NSW, Australia, 3MIT,
Cambridge, MA, United States.
04.01
Lactobacillus paracasei and Lactobacillus reuteri inhibit
TNF-α production by Helicobacter-activated murine macrophages
J. A. Peña1,2, J. Versalovic1,2;
1Baylor College of Medicine, Houston, TX, United States,
2Texas Children's Hospital, Houston, TX, United States.
08.03
Helicobacter hepaticus-induced colitis is diminished by
co-infection with Lactobacillus
J. A. Peña1,2, A. B. Rogers3, Z. Ge3,
J. G. Fox3, J. Versalovic1,2;
1Baylor College of Medicine, Houston, TX, United States,
2Texas Children's Hospital, Houston, TX, United States, 3Massachusetts
Institute of Technology, Cambridge, MA, United States. |
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| 15.30 – 16.00 |
Coffee Break |
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| 16.00 – 17.00 |
Poster Discussion |
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13.30 – 17.00
Room K1 |
Workshop 3:
Microbiology, Probiotics and Genomics |
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| Chairpersons: |
Johannes Kusters, The
Netherlands
Britta Björkholm, Sweden |
| Reporter: |
Agnes Labigne, France |
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01.01
Quorum sensing in Helcobacter pylori and its association with
infectivity to Mongolian gerbil
S. Kamiya1, T. Osaki1, T. Hanawa1,
S. Nakagawa1,2, I. Ohshio1,3, H. Yamaguchi1;
1Kyorin University, Mitaka, Japan, 2Aventis Pharma
Ltd., Tokyo, Japan, 3Nippon Soda Co. Ltd., Odawara, Japan.
01.02
A therapeutic target in the de novo purine nucleotide biosynthesis
pathway of Helicobacter pylori.
A. Menard1, B. Bergey1, P. Avenaud1,
F. Megraud1, G. L. Mendz2;
1Universite Victor Segalen Bordeaux II, Bordeaux, France,
2The University of New South Wales, Sydney, Australia.
01.03
LPS diversity in intra-patient isolates of Helicobacter pylori
C. Nilsson1,2, A. Lundin1,2, L. Engstrand1,2,
S. Normark1;
1Microbiology and Tumorbiology Center, Karolinska Institutet,
Stockholm, Sweden, 2Swedish Institute for Infectious Disease
Control, Solna, Sweden.
01.04
Arginase Supports the Acid Tolerance of Helicobacter pylori.
G. L. Mendz1, D. J. McGee2, J. Zabaleta3,
A. C. Ochoa2;
1The University of New South Wales, Sydney, Australia, 2University
of South Alabama, Mobile, AL, United States, 3Louisiana State
University, New Orleans, LA, United States.
02.01
Transcriptome analysis of the Helicobacter pylori Fur- and
iron-regulons: Fur-mediated regulation of superoxide dismutase
F. D. Ernst1,2,3, A. H. M. van Vliet1, B.
Waidner3, J. Stoof1, U. Mäder2, J. G.
Kusters1, M. Kist3, S. Bereswill3, G.
Homuth2;
1Erasmus MC, Rotterdam, Netherlands, 2University
of Greifswald, Greifswald, Germany, 3University Hospital of
Freiburg, Freiburg, Germany.
02.02
Small RNA genes in the convergently transcribed intergenic regions of
the Helicobacter pylori genome
Q. Dong, R. Mcloughlin, H. Windle, C. O'Morain, M. Buckley;
Adelaide & Meath Hospital, Dublin, Ireland.
01.07
Characterization of Lactobacillus strains for antagonistic
activity against Helicobacter pylori
P. Mastromarino, L. Serrao, T. Melillo, P. Goldoni;
University of Rome, Rome, Italy. |
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| 15.30 – 16.00 |
Coffee Break |
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| 16.00 – 17.00 |
Poster Discussion |
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13.30 – 17.00
Room K2 |
Workshop 4: Rescue and
novel treatments |
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| Chairpersons: |
Colm O’Morain, Ireland
Francis Mégraud, France |
| Reporter: |
Franco Bazzoli, Italy |
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16.01
Real-time PCR directly from gastric biopsies is an accurate method for
quantitative detection of H. pylori coupled with detection of
clarithromycin (CLA) resistance (R) mutations.
J. Tankovic1, D. Lamarque2, C. Lascols3,
J. Costa4, C. Copie3, J. Petit1, J.
Delchier3;
1Hôpital Saint Antoine, Paris, France, 2Hôpital
Bichat, Paris, France, 3Hôpital H. Mondor, Créteil, France,
4Hôpital Américain de Paris, Paris, France.
16.05
Helicobacter pylori eradication practice at primary and secondary care
level: a 3-year follow-up
A. Qasim, O. Thornton, M. Dobson, S. Sebastian, R. McLoughlin, M.
Buckley, H. O'Connor, C. O'Morain;
Adelaide and Meath Hospital, Tallaght, Trinity College, Dublin, Ireland.
16.09
One-week triple therapy with esomeprazole, levofloxacin and amoxicillin
is effective for eradication of Helicobacter pylori sensitive or
resistant to metronidazole and/or clarithromycin
S. Miehlke1, A. Madisch1, E. Bästlein2,
W. Schneider-Brachert3, C. Hänel1, C. Haferland4,
P. Piehler5, M. Buchner6, E. Meier7, F.
Trump8, D. Antos9, M. Stolte10, N. Lehn11,
E. Bayerdörffer12;
1Medical Department I, Technical University Hospital,
Dresden, Germany, 2Gastroenterologist in private practice,
Cologne, Germany, 3Institute for Medical Microbiology,
University Hospital, Regensburg, Germany, 4Gastroenterologist
in private practice, Görlitz, Germany, 5Medical Department,
Helios Hospital, Kitzbühl, Austria, 6Gastroenterologist in
private practice, Ribnitz-Damgarten, Germany, 7Gastroenterologist
in private practice, Amberg, Germany, 8Medical Department ,
Community Hospital, Pegnitz, Germany, 9Clinic of Pediatric
Disease, Ludwig-Maximilians University Hospital, Munich, Germany,
10Institute for Pathology, Klinikum Bayreuth, Bayreuth, Germany,
11Institute for Medical Microbiology, University Hospital,
Regensburg, Germany, 12Center of Internal Medicine,
University Hospital, Marburg, Germany.
16.11
Impact of Bacillus clausii supplementation on anti-Helicobacter
pylori therapy-telated side effects: a randomized double- bind
placebo –controlled study
E. C. Nista, M. Candelli, I. A. Cazzato, E. Carloni, M. Gabrielli,
L. Fini, A. Di Giorgio, M. A. Zocco, F. Franceschi, R. Finizio, L.
Santarelli, P. Pola, G. Gasbarrini, A. Gasbarrini;
UCSC, Rome, Italy.
16.43
Helicobacter pylori eradication in routine clinical practice
G. Lindberg, A. Dlugosz;
Karolinska Institutet, Stockholm, Sweden.
16.48
Empirical Helicobacter pylori “rescue” therapy after failure of
two eradication treatments
J. P. Gisbert, J. L. Gisbert, S. Marcos, J. Pajares;
La Princesa University Hospital, Madrid, Spain.
16.14
Towards a new therapeutic target: Helicobacter pylori flavodoxin
M. Bueno1,2, N. Cremades2,1, M. Toja3,
J. Sancho2,1;
1University of Zaragoza, Zaragoza, Spain, 2Biocomputation
and Complex Systems Physics Institute, Zaragoza, Spain, 3Operon
S.A., Cuarte de Huerva (Zaragoza), Spain. |
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| 15.30 – 16.00 |
Coffee Break |
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| 16.00 – 17.00 |
Poster Discussion |
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17.00 - 19.00
K11 |
Diagnostics and
Molecular Genetics of Helicobacter |
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| Chairpersons: |
Hilpi Rautelin, Finland
Å. Ljungh, Sweden |
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Part 1: Diagnostics |
| 17.00 |
Introduction - Invasive
vs non-invasive methods
H. Rautelin, Finland |
| 17.10 |
Qualitative vs
quantitative ELISA methods
H. Rautelin, Finland |
| 17.20 |
Immunoblot for detection
of virulence markers
Å. Ljungh, Sweden |
| 17.35 |
Faecal antigen tests
A. Makristathis, Austria |
| 17.50 |
UBT in clinical praxis
B. Gold, United States |
| 18.00 |
Non-invasive methods for
the diagnosis of atrophy
P. Sipponen, Finland |
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Part 2: Molecular
Genetics |
| 18.15 |
Pyrosequencing for rapid
diagnosis and genotyping
H.-J. Monstein |
| 18.30 |
Real-time PCR as a
diagnostic alternative
J. Versalovic, United States |
| 18.45 |
Microarrays - future
typing tools?
B. Björkholm, Sweden |
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