Programme

Friday, September 5, 2003 - Thursday, September 4, 2003 - Saturday, September 6, 2003

8.30 – 9.00
Room K1/K2
Helicobacter pylori and cancer
   
Chairpersons: Anthony Axon, United Kingdom
Olof Nyrén , Sweden
   
  State of the Art lecture
D.Y. Graham, United States
   
9.00 – 12.05 Focus/Round Tables
  Epidemiology
D. Forman, United Kingdom

Host susceptibility
M. Blaser, United States

Microbial Factors
S. Normark, Sweden

   
10.15 – 10.45 Coffee Break
   
  Cell Biology
P. Falk, Sweden

Pathology
R. Genta, Switzerland

Clinic
K. McKoll, United Kingdom

   
12.05 – 13.30 Individual Lunch & Poster Viewing
   
13.30 – 17.00
Room K2
Workshop 5: Clinical and Epidemiological issues
   
Chairpersons:
 
Gerardo Nardone, Italy
Ernst J. Kuipers, The Netherlands
Reporter: David Forman, United Kingdom
   
 

05.04
Long-standing Gastric Mucosal Barrier Dysfunction in Mongolian Gerbils with Helicobacter pylori-induced Gastritis
Y. Sun1, J. D. Söderholm1, F. Petersson2, K. Borch1;
1Division of Surgery, Department of Biomedicine and Surgery, Faculty of Health Sciences, Linköping, Sweden, 2Pathology Research Department, Ryhov Hospital, Jönköping, Sweden.

06.01
The prevalence and transmission of Helicobacter Pylori in a large population based screening programme in Norway. The Nord-Trřndelag healthstudy (HUNT)
K. Hveem, Ř. Krüger;
HUNT Research Centre, Verdal, Norway.

06.02
Assessment of acquisition of Helicobacter pylori in Bangladeshi children by serologic methods
G. I. Perez-Perez1, A. Z. Olivares1, R. Sack2, K. Hasan3, S. Saker3, P. Bardham3, M. J. Blaser1,4;
1New York University School of Medicine, New York, NY, United States, 2Johns Hopkins University, Baltimore, MD, United States, 3Institute of Cholera and Diarrhea Diseases Research, Dhaka, Bangladesh, 4VA Medical Affairs, New York, NY, United States.

06.03
Helicobacter pylori acquisition in infancy: first results of a prospective birth cohort study from Germany
D. Rothenbacher1, M. Weyermann1, G. Bode1, G. Adler2, H. Brenner1;
1Dept. of Epidemiology/German Centre for Research on Ageing, Heidelberg, Germany, 2Dept. of Internal Medicine I, Ulm, Germany.

06.04
Concordance of Helicobacter pylori strains within families
M. Kivi, Y. Tindberg, C. Bengtsson, L. Engstrand, M. Granström;
Karolinska Institutet, Stockholm, Sweden.

11.15
TNF-Alpha and LTB-4 are involved in the pathogenesis of gastroduodenal damage induced by low-dose aspirin and Helicobacter pylori infection.
G. Treiber, T. Wex, P. Malfertheiner;
Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

12.10
H. pylori-positive or -negative carriers of interleukin-1 gene polymorphisms are protected against GERD
D. M. M. Queiroz, J. B. Guerra, A. Santos, A. G. Oliveira, A. M. C. Rocha, A. M. F. Nogueira, M. M. D. A. Cabral, C. A. Oliveira, G. A. Rocha;
Universidade Federal de Minas Gerais/Faculade de Medicina, Belo Horizonte, Brazil.

   
15.30 – 16.00 Coffee Break
   
16.00 – 17.00 Poster Discussion
   
13.30 – 17.00
Room K11
Workshop 6: Extragastric benign and malignant Diseases
   
Chairpersons: James Fox, United States
Anthony Moran , Ireland
Reporter: Antonio Gasbarrini, Italy
   
 

9.01
Detection of enterohepatic Helicobacter species in patients suffering from inflammatory bowel diseases
U. R. M. Bohr, B. Glasbrenner, A. Primus, A. Zagoura, T. Wex, P. Malfertheiner;
Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.

9.02
Nickel-responsive induction of urease activity is restricted to gastric Helicobacter species
A. H. M. van Vliet, J. Stoof, E. J. Kuipers, J. G. Kusters;
Erasmus MC, Rotterdam, Netherlands.

9.05
Two-dimensional gel-electrophoresis and immunoblot analysis of cell-surface proteins of non-gastric Helicobacter
O. Fedkiv, T. Wadstrom, I. Nilsson, A. Ljungh;
Medical Microbiology, Dermatology and Infection, Lund University, Lund, Sweden.

9.07
Preliminary analysis of the lipopolysaccharides (LPSs) of human and chicken isolates of Helicobacter pullorum
A. P. Moran1, A. V. Perepelov2,3, Y. A. Knirel2,3, S. O. Hynes4, T. Wadstrom4, P. E. Jansson2;
1National University of Ireland, Galway, Galway, Ireland, 2Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden, 3N.D. Zelinsky Institute of Organic Chemistry, Russian of Academy of Sciences, Moscow, Russian Federation, 4University of Lund, Lund, Sweden.

9.12
Prevalence of entero-hepatic helicobacters in Crohn’s disease: preliminary study.
F. Zerbib1,2, D. Laharie3,1, C. Asencio1, A. Ménard1, H. Lamouliatte2, P. Couzigou3, F. Mégraud1;
1Université Victor Segalen Bordeaux 2, Bordeaux, France, 2Hôpital Saint André, Bordeaux, France, 3Hôpital Haut Lévęque, Bordeaux, France.

13.02
A genetic basis for hepatocellular cancer: dominant responsiveness in Helicobacter hepaticus induced liver cancer in F1 hybrid B6AF1 male mice
A. Garcia, A. B. Rogers, M. Ihrig, J. G. Fox;
Massachusetts Institute of Technology, Cambridge, MA, United States.

13.03
H. pylori infection and risk of cirrhosis in patients with hepatitis C virus
G. A. Rocha1, S. M. S. Cinque1, A. M. C. Rocha1, A. G. Oliveira1,2, A. Godoy3, H. Tanno3, D. M. M. Queiroz1;
1Universidade Federal de Minas Gerais/Faculdade de Medicina, Belo Horizonte, Brazil, 2Faculdade de Medicina do Triângulo Mineiro, Uberaba, Brazil, 3Universidad Nacional de Rosario, Rosario, Argentina.

13.07
Link between Helicobacter and chronic gall bladder disease?
E. Apostolov1,2, Y. Gaydar2, W. Abu Al-Soud1, I. Kornilovs´ka1, V. Usenko3, V. Lyzogubov3, A. Ljungh1, T. Wadstrom1;
1Medical Microbiology, Dermatology and Infection, Lund University, Lund, Sweden, 2Dept Pathology, Inst Gastroenterology of Academy of Med Science of Ukraine, Dnipropetrovsk, Ukraine, 3Morphological Laboratory BIONTEC, Dnipropetrovsk, Ukraine.

14.03
A possible role of Lewis determinants of H. pylori LPS in the pathogenesis of atherosclerosis.
M. Chmiela1, T. Rechcinski2, A. Moran3, A. Miszczak1, M. Krzeminska - Pakula2, M. Wieckowska - Szakiel1, L. Bak - Romaniszyn4, I. Planeta _ Malecka4, W. Rudnicka1;
1University of Lodz, Lodz, Poland, 2Medical University in Lodz, Lodz, Poland, 3National University of Ireland, Galway, Ireland, 4Institute Mother and Child Health Centre, Lodz, Poland.

14 05
Cag-A positive cytotoxic H. pylori strains: a link between plaque instability and atherosclerotic stroke ?
M. Gabrielli, A. Santoliquido, V. Cicconi, M. Candelli, E. C. Nista, R. Finizio, M. Serricchio, P. Tondi, G. Gasbarrini, P. Pola, A. Gasbarrini;
Catholic University, Rome, Italy.

   
15.30 – 16.00 Coffee Break
   
16.00 – 17.00 Poster Discussion
   
13.30 – 17.00
Room K1
Workshop 7: Microbial Pathogenesis
   
Chairpersons: Thomas Borén, Sweden
Michael Naumann, Germany
Reporter: Steffen Backert, Germany
   
 

03.03
A novel apoptosis-inducing protein from Helicobacter pylori
K. Shibayama, K. Kamachi, T. Yagi, K. Yamane, Y. Doi, N. Shibata, H. Kato, Y. Arakawa;
National Institute of Infectious Diseases, Tokyo, Japan.

03.04
Functional Adaptation of BabA Adherence and Ethnic Tropism by Helicobacter pylori
M. Hurtig1, N. Roche2, G. Dailide3, S. Vikström1, A. Arnqvist1, D. Ilver2, S. Lindén4, U. Nilsson5, B. Velapatińo6, R. Gilman6, T. Alarcon7, M. López-Brea7, T. Nakazawa8, A. Parkinson9, J. Fox10, P. Correa11, G. Perez-Perez12, M. Blaser12, S. Normark13, I. Carlstedt4, S. Teneberg2, D. Berg3, T. Borén1;
1Department of Odontology, Oral Microbiology, Umeĺ University, Umeĺ, Sweden, 2Institute of Medical Biochemistry, Göteborg University, Göteborg, Sweden, 3Department of Molecular Microbiology, Washington University Medical School, St. Louis, MO, United States, 4Department of Cell and Molecular Biology, Lund University, Lund, Sweden, 5Department of Organic Chemistry, The Lund Institute of Technology, University of Lund, Lund, Sweden, 6Department of Pathology, Universidad Peruana Cayetano Heredia, Lima, Peru, 7Department of Microbiology, Hospital de la Princesa, Madrid, Spain, 8Department of Microbiology, Yamaguchi University School of Medicine, Yamaguchi, Japan, 9Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK, United States, 10Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, United States, 11Louisiana State University Medical Center, New Orleans, AL, United States, 12Department of Medicine, New York University School of Medicine, New York, NY, United States, 13Microbiology and Tumorbiology Center (MTC), Karolinska Institute, Stockholm, Sweden.

03.06
Modification in the Outer Membrane Proteins of Helicobacter pylori During Experimental Infection of Rhesus Macaques
J. V. Solnick1, L. M. Hansen1, N. Salama2, J. Boonjakuakul1, M. Syvanen1, S. Falkow3;
1University of California, Davis, Davis, CA, United States, 2Fred Hutchinson Cancer Research Center, Seattle, WA, United States, 3Stanford University School of Medicine, Stanford, CA, United States.

03.12
An H. pylori factor inhibits growth of leukemia cells by inducing cell cycle arrest
M. Gerhard, C. Schmees, M. Sander, P. Voland, C. K. Prinz;
II. Medical Department, Munich, Germany.

03.21
Gastrointestinal diseases in Mongolian Gerbils due to Helicobacter pylori infection: role of cag pathogenicity island
G. E. Rieder1, E. Weiss1, J. L. Merchant2, R. Haas1;
1Max-von-Pettenkofer Institute, Department of Hygiene and Medical Microbiology, Munich, Germany, 2Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.

03.11
Role of Interferon-Stimulated Responsive Element-Like Element in Helicobacter pylori-Induced Interleukin-8 Gene Transcription
Y. Yamaoka1,2, T. Kudo1,2, H. Lu1,2, A. Casola3, A. R. Brasier3, D. Y. Graham1,2;
1VA Medical Center, Houston, TX, United States, 2Baylor College of Medicine, Houston, TX, United States, 3University of Texas Medical Branch, Galveston, TX, United States.

18.05
Profiling of Helicobacter pylori infection induced gene expression
S. Myllykangas1,2,3, O. Monni4,3, H. Rautelin5,2,3, S. Knuutila2,1,3;
1Departments of Pathology and Medical Genetics, Helsinki, Finland, 2Haartman Institute, Helsinki, Finland, 3University of Helsinki and Helsinki University Central Hospital Laboratory Diagnostics, Helsinki, Finland, 4Biomedicum Biochip Center, Helsinki, Finland, 5Department of Bacteriology and Immunology, Helsinki, Finland.

   
15.30 – 16.00 Coffee Break
   
16.00 – 17.00 Poster Discussion
   
13.30 – 17.00
Room K21
Workshop 8: Preneoplastic and neoplastic diseases
   
Chairpersons: Pentti Sipponen, Finland
Heidi-Ingrid Maaros, Estonia
Reporter: Theodore Rokkas, Greece
   
 

10.17
Molecular and immunohistochemical evaluation of the expression of telomerase in gastric carcinomas: Correlation with Hp infection
A. Karameris1, T. A. Rokkas2;
1Histopathology Department, 417 VA Hospital, Athens, Greece, 2Gastroenterology Clinic, Henry Dunant Hospital, Athens, Greece.

07.05
Evidence for downregulation of the Sonic Hedgehog-Pathway in atrophic gastritis, intestinal metaplasia and gastric cancer
G. Faller, A. Dimmler, T. Kirchner;
Insitute of Pathology, Erlangen, Germany.

10.16
The frequency of IL-1 gene polymorphisms in Sowetan subjects and their relationship with H. pylori associated disease.
H. M. Mitchell1, R. Ally2, S. Egan1, R. Mailvaganam1, M. Gengos1, I. Segal1;
1University of NSW, Sydney, NSW, Australia, 2Chris Hani Baragwanath Hospital, Johannesburg, South Africa.

07.16
Prevalence of and risk factors for atrophic corpus gastritis
M. Held1, H. Rautelin2, S. Sandin1, B. Stegmayr3, G. Hallmans4, L. Engstrand5, O. Nyrén1;
1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, 2Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland, 3Department of Public Health and Clinical Medicine, University of Umeĺ, Umeĺ, Sweden, 4Department of Public Health and Clinical Medicine, Nutritional Research, University of Umeĺ, Umeĺ, Sweden, 5Swedish Institute for Infectious Disease Control, Stockholm, Sweden.

07.07
Detection of Helicobacter pylori related premalignant lesions at screening in first degree relatives of gastric cancer
S. Sebastian, W. Hall, P. Crotty, H. O`Connor, M. Buckley, C. O`Morain;
Adelaide and Meath Hospital, Dublin, Ireland.

07.01
H.pylori related atrophic gastritis is a common cause of low vitamin B12 and high homocysteine in serum in anelderly male population
P. Sipponen, F. Laxén, K. Huotari, M. Härkönen;
HUCH, Jorvi Hospital, Espoo, Finland.

07.15
Evaluation of Helicobacter pylori status and serum pepsinogen levels in Barrett’s esophagus and gastric intestinal metaplasia
C. Portal-Celhay1, G. I. Perez-Perez1, A. Z. Olivares1, F. Francois1, S. Foo2, E. Bini1,3, M. J. Blaser1,3;
1New York University School of Medicine, New York, NY, United States, 2New York University, Downtown Hospital, New York, NY, United States, 3VA Medical Affairs, New York, NY, United States.

   
15.30 – 16.00 Coffee Break
   
16.00 – 17.00 Poster Discussion
   
19.00 Get together at the Vasa Museum
 
 

Friday, September 5, 2003 - Thursday, September 4, 2003 - Saturday, September 6, 2003